Regulatory Network in Protein Phosphorylation
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Kinase: IRAK2 interleukin-1 receptor-associated kinase 2

Group: TKL      Family: IRAK      

Description: interleukin-1 receptor-associated kinase 2

Gene Symbol: IRAK2

Synonyms: IRAK-2, MGC150550

UniprotKB/SwissProt: IRAK2_HUMAN (O43187)

Function: Binds to the IL-1 type I receptor following IL-1 engagement, triggering intracellular signaling cascades leading to transcriptional up-regulation and mRNA stabilization.

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase family IRAK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1IRAK1IRAK1_HUMANInterleukin-1 receptor-associated kinase 1 (EC 2.7.11.1) (IRAK-1). 9Show
2STAT3STAT3_HUMANSignal transducer and activator of transcription 3 (Acute-phaseresponse factor). 1Show