Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinome Table]
Kinase: IRAK3 interleukin-1 receptor-associated kinase 3

Group: TKL      Family: IRAK      

Description: interleukin-1 receptor-associated kinase 3

Gene Symbol: IRAK3

Synonyms: IRAK-M

UniprotKB/SwissProt: IRAK3_HUMAN (Q9Y616)

Function: Inhibits dissociation of IRAK1 and IRAK4 from the Toll- like receptor signaling complex by either inhibiting the phosphorylation of IRAK1 and IRAK4 or stabilizing the receptor complex (By similarity).

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase family IRAK

 No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1IRAK1IRAK1_HUMANInterleukin-1 receptor-associated kinase 1 (EC (IRAK-1). 9Show
2STAT3STAT3_HUMANSignal transducer and activator of transcription 3 (Acute-phaseresponse factor). 1Show