Regulatory Network in Protein Phosphorylation
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Kinase: TESK1 testis-specific kinase 1

Group: TKL      Family: LISK      Subfamily: TESK

Description: testis-specific kinase 1

Gene Symbol: TESK1

Synonyms: -

UniprotKB/SwissProt: TESK1_HUMAN (Q15569)

Function: Dual specificity protein kinase activity catalyzing autophosphorylation and phosphorylation of exogenous substrates on both serine/threonine and tyrosine residues. Probably plays a central role at and after the meiotic phase of spermatogenesis (By similarity).

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase TESK1

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase-specific phosphorylation sitesView
1CFL1COF1_HUMANCofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18). 2Show
2TESK1TESK1_HUMANDual specificity testis-specific protein kinase 1 (EC 2.7.12.1)(Testicular protein kinase 1). 1Show



The substrate proteins of kinase family TESK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1CFL1COF1_HUMANCofilin-1 (Cofilin, non-muscle isoform) (18 kDa phosphoprotein) (p18). 3Show
2DSTNDEST_HUMANDestrin (Actin-depolymerizing factor) (ADF). 1Show
3TESK1TESK1_HUMANDual specificity testis-specific protein kinase 1 (EC 2.7.12.1)(Testicular protein kinase 1). 1Show