|Group: TKL Family: LRRK |
Description: leucine-rich repeat kinase 2
Gene Symbol: LRRK2
Synonyms: PARK8, RIPK7, ROCO2
UniprotKB/SwissProt: LRRK2_HUMAN (Q5S007)
Function: Probable protein kinase whose role is not yet known. May play a role in the phosphorylation of proteins central to Parkinson disease. May also have GTPase activity.
Subcellular Localization: Cytoplasm. Membrane; Peripheral membrane protein. Note=Localized in the cytoplasm and associated with cellular membrane structures. Associates with the mitochondrial outer membrane.