Regulatory Network in Protein Phosphorylation
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Kinase: MLK4 mixed lineage kinase 4

Group: TKL      Family: MLK      Subfamily: MLK

Description: mixed lineage kinase 4

Gene Symbol: KIAA1804

Synonyms: MLK4, RP5-862P8.2, dJ862P8.3

UniprotKB/SwissProt: M3KL4_HUMAN (Q5TCX8)

Function: Activates the JUN N-terminal pathway (By similarity).

Subcellular Localization:

Protein Domain:

The substrate proteins of kinase family MLK

No.Gene NameUniProtKB IDProtein DescriptionNumber of kinase family-specific phosphorylated sitesView
1CEACAM1CEAM1_HUMANCarcinoembryonic antigen-related cell adhesion molecule 1 precursor(Biliary glycoprotein 1) (BGP-1) (CD66 antigen) (CD66a antigen). 1Show
2MAP3K11M3K11_HUMANMitogen-activated protein kinase kinase kinase 11 (EC lineage kinase 3) (Src-homology 3 domain-containing proline-rich kinase). 3Show
3MAP3K9M3K9_HUMANMitogen-activated protein kinase kinase kinase 9 (EC (Mixedlineage kinase 1). 1Show
4MAP2K4MP2K4_HUMANDual specificity mitogen-activated protein kinase kinase 4(EC (MAP kinase kinase 4) (JNK-activating kinase 1) (c-JunN-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1). 1Show