Regulatory Network in Protein Phosphorylation
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Kinase: BMPR1A bone morphogenetic protein receptor, type IA

Group: TKL      Family: STKR      Subfamily: Type1

Description: bone morphogenetic protein receptor, type IA

Gene Symbol: BMPR1A

Synonyms: ACVRLK3, ALK3, CD292

UniprotKB/SwissProt: BMR1A_HUMAN (P36894)

Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4.

Subcellular Localization: Membrane; Single-pass type I membrane protein.

Protein Domain:
PDB:1ES7