|Group: TKL Family: STKR Subfamily: Type2|
Description: anti-Mullerian hormone receptor, type II
Gene Symbol: AMHR2
Synonyms: AMHR, MISRII
UniprotKB/SwissProt: AMHR2_HUMAN (Q16671)
Function: On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for anti-Muellerian hormone.
Subcellular Localization: Membrane; Single-pass type I membrane protein.