|Description: Proline-rich AKT1 substrate 1 (40 kDa proline-rich AKT substrate).|
Ensembl ID: ENSG00000204673
UniprotKB/SwissProt: AKTS1_HUMAN (Q96B36)
Function: May play an important role in phosphatidylinositol 3- kinase (PI3K)-AKT1 survival signaling. Substrate for AKT1 phosphorylation, but can also be activated by AKT1-independent mechanisms. Its role in survival signaling pathways may be modulated by oxidative stress. May also play a role in nerve growth factor-mediated neuroprotection.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm, cytosol (By similarity). Note=Found in the cytosolic fraction of the brain (By similarity).