Regulatory Network in Protein Phosphorylation
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Substrate: ATXN1

Description: Ataxin-1 (Spinocerebellar ataxia type 1 protein).

Synonyms: ATX1, SCA1

Ensembl ID: ENSG00000124788

UniprotKB/SwissProt: ATX1_HUMAN (P54253)

Function: Binds RNA in vitro. May be involved in RNA metabolism. The expansion of the polyglutamine tract may alter this function.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (By similarity). Nucleus. Note=Colocalizes with USP7 in the nucleus.
PDB:1OA8
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of ATXN1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1ATXN1ATX1_HUMANT236APGLI T PGSPP 27.00% Phospho.ELM 7.0View   
2ATXN1ATX1_HUMANS239LITPG S PPPAQ 35.12% Phospho.ELM 7.0View   
3ATXN1ATX1_HUMANS776RKRRW S APESR 31.94%AKT_group Phospho.ELM 7.0 ViewAnalyzing
4ATXN1ATX1_HUMANS776RKRRW S APESR 31.94%AKT1 HPRD:03333(in vitro;in vivo)  ViewAnalyzing