|Description: Sphingosine 1-phosphate receptor Edg-1 (Sphingosine 1-phosphatereceptor 1) (S1P1).|
Ensembl ID: ENSG00000170989
UniprotKB/SwissProt: EDG1_HUMAN (P21453)
Function: Receptor for the lysosphingolipid sphingosine 1- phosphate (S1P). S1P is a bioactive lysophospholipid that elicits diverse physiological effect on most types of cells and tissues. This inducible epithelial cell G-protein-coupled receptor may be involved in the processes that regulate the differentiation of endothelial cells. Seems to be coupled to the G(i) subclass of heteromeric G proteins.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein.