Regulatory Network in Protein Phosphorylation
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Substrate: FANCA

Description: Fanconi anemia group A protein (Protein FACA).

Synonyms: FAA, FACA, FANCH

Ensembl ID: ENSG00000187741

UniprotKB/SwissProt: FANCA_HUMAN (O15360)

Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Note=The major form is nuclear. The minor form is cytoplasmic.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of FANCA

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1FANCAFANCA_HUMANS849SLCKF S SQSRD 16.98% Swiss-Prot 55.0 View   
2FANCAFANCA_HUMANS850LCKFS S QSRDT 34.99% Swiss-Prot 55.0 View   
3FANCAFANCA_HUMANS858RDTLC S CLSPG 22.62% Swiss-Prot 55.0 View   
4FANCAFANCA_HUMANS1149RSRDP S LMVDF 33.13%AKT_group Phospho.ELM 7.0 ViewAnalyzing
5FANCAFANCA_HUMANS1149RSRDP S LMVDF 33.13%AKT1 HPRD:06186(in vitro)  ViewAnalyzing
6FANCAFANCA_HUMANS1449PDADL S QEPHL 32.80% Swiss-Prot 55.0 View