Regulatory Network in Protein Phosphorylation
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Substrate: FOXO1

Description: Forkhead box protein O1 (Forkhead box protein O1A) (Forkhead inrhabdomyosarcoma).

Synonyms: FKHR, FOXO1A

Ensembl ID: ENSG00000150907

UniprotKB/SwissProt: FOXO1_HUMAN (Q12778)

Function: Transcription factor.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Nucleus. Note=Shuttles between cytoplasm and nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of FOXO1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1FOXO1FOXO1_HUMANT24RPRSC T WPLPR 31.22%AKT1 HPRD:00645(in vitro;in vivo)  ViewAnalyzing
2FOXO1FOXO1_HUMANT24RPRSC T WPLPR 31.22%AKT1(PKB)  Swiss-Prot 55.0  ViewAnalyzing
3FOXO1FOXO1_HUMANT24RPRSC T WPLPR 31.22%SGK_group Phospho.ELM 7.0 ViewAnalyzing
4FOXO1FOXO1_HUMANT24RPRSC T WPLPR 31.22%AKT_group Phospho.ELM 7.0 ViewAnalyzing
5FOXO1FOXO1_HUMANS256RRRAA S MDNNS 26.19%SGK_group Phospho.ELM 7.0 ViewAnalyzing
6FOXO1FOXO1_HUMANS256RRRAA S MDNNS 26.19%AKT1(PKB)  Swiss-Prot 55.0  ViewAnalyzing
7FOXO1FOXO1_HUMANS256RRRAA S MDNNS 26.19%AKT1 HPRD:00645(in vitro;in vivo)  ViewAnalyzing
8FOXO1FOXO1_HUMANS256RRRAA S MDNNS 26.19%PAK1 HPRD:00645(in vivo)  ViewAnalyzing
9FOXO1FOXO1_HUMANS256RRRAA S MDNNS 26.19%AKT_group Phospho.ELM 7.0 ViewAnalyzing
10FOXO1FOXO1_HUMANS319RPRTS S NASTI 35.48%SGK_group Phospho.ELM 7.0 ViewAnalyzing
11FOXO1FOXO1_HUMANS319RPRTS S NASTI 35.48%AKT_group Phospho.ELM 7.0 ViewAnalyzing
12FOXO1FOXO1_HUMANS319RPRTS S NASTI 35.48%AKT1 HPRD:00645(in vitro;in vivo)  ViewAnalyzing
13FOXO1FOXO1_HUMANS319RPRTS S NASTI 35.48%AKT1(PKB)  Swiss-Prot 55.0  ViewAnalyzing
14FOXO1FOXO1_HUMANS322TSSNA S TISGR 30.44%AKT_group Phospho.ELM 7.0 ViewAnalyzing
15FOXO1FOXO1_HUMANS322TSSNA S TISGR 30.44%DYRK1A Phospho.ELM 7.0  ViewAnalyzing
16FOXO1FOXO1_HUMANS322TSSNA S TISGR 30.44%CK1a(CK1 alpha) Phospho.ELM 7.0 ViewAnalyzing
17FOXO1FOXO1_HUMANS322TSSNA S TISGR 30.44%CK1g1 HPRD:00645(in vivo)  ViewAnalyzing
18FOXO1FOXO1_HUMANS325NASTI S GRLSP 20.25%GSK_group Phospho.ELM 7.0 ViewAnalyzing
19FOXO1FOXO1_HUMANS325NASTI S GRLSP 20.25%GSK3B HPRD:00645(in vivo)  ViewAnalyzing
20FOXO1FOXO1_HUMANS325NASTI S GRLSP 20.25%CK1a(CK1 alpha) Phospho.ELM 7.0 ViewAnalyzing
21FOXO1FOXO1_HUMANS325NASTI S GRLSP 20.25%AKT_group Phospho.ELM 7.0 ViewAnalyzing
22FOXO1FOXO1_HUMANS329ISGRL S PIMTE 15.83%DYRK1A Swiss-Prot 55.0   ViewAnalyzing
23FOXO1FOXO1_HUMANS329ISGRL S PIMTE 15.83%DYRK1A HPRD:00645(in vitro;in vivo)  ViewAnalyzing
24FOXO1FOXO1_HUMANS329ISGRL S PIMTE 15.83%DYRK1A Phospho.ELM 7.0  ViewAnalyzing
25FOXO1FOXO1_HUMANT467LKELL T SDSPP 43.01% Swiss-Prot 55.0 (Similarity)View   
26FOXO1FOXO1_HUMANS468KELLT S DSPPH 35.74% Swiss-Prot 55.0 (Similarity)View   
27FOXO1FOXO1_HUMANS505PNSVM S TYGSQ 19.13% Swiss-Prot 55.0 View   
28FOXO1FOXO1_HUMANS509MSTYG S QASHN 16.50% Swiss-Prot 55.0 View