|Description: FKBP12-rapamycin complex-associated protein (FK506-binding protein 12-rapamycin complex-associated protein 1) (Rapamycin target protein)(RAPT1) (Mammalian target of rapamycin) (mTOR).|
Synonyms: FRAP, FRAP2
Ensembl ID: ENSG00000198793
UniprotKB/SwissProt: FRAP_HUMAN (P42345)
Function: Acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. Part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: