|Description: Dual specificity mitogen-activated protein kinase kinase 4(EC 220.127.116.11) (MAP kinase kinase 4) (JNK-activating kinase 1) (c-JunN-terminal kinase kinase 1) (JNKK) (SAPK/ERK kinase 1) (SEK1).|
Synonyms: JNKK1, MKK4, PRKMK4, SERK1
Ensembl ID: ENSG00000065559
UniprotKB/SwissProt: MP2K4_HUMAN (P45985)
Function: Dual specificity kinase that activates the JUN kinases MAPK8 (JNK1) and MAPK9 (JNK2) as well as MAPK14 (p38) but not MAPK1 (ERK2) or MAPK3 (ERK1).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: