Regulatory Network in Protein Phosphorylation
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Substrate: PDE3B

Description: cGMP-inhibited 3',5'-cyclic phosphodiesterase B (EC (CyclicGMP-inhibited phosphodiesterase B) (CGI-PDE B) (CGIPDE1) (CGIP1).

Ensembl ID: ENSG00000152270

UniprotKB/SwissProt: PDE3B_HUMAN (Q13370)

Function: May play a role in fat metabolism.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Multi-pass membrane protein (Potential).
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PDE3B

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PDE3BPDE3B_HUMANS295RPRRR S SCVSL 26.69%AKT1 HPRD:03626(in vitro;in vivo)  ViewAnalyzing
2PDE3BPDE3B_HUMANS318IFRRP S LPCIS 43.03%PKA_group Phospho.ELM 7.0 ViewAnalyzing
3PDE3BPDE3B_HUMANS318IFRRP S LPCIS 43.03%PKACa HPRD:03626(in vitro;in vivo)  ViewAnalyzing
4PDE3BPDE3B_HUMANS318IFRRP S LPCIS 43.03%AKT1 HPRD:03626(in vitro;in vivo)  ViewAnalyzing
5PDE3BPDE3B_HUMANS442QLRRS S GTSGL 44.25%AKT1 HPRD:03626(in vitro)  ViewAnalyzing
6PDE3BPDE3B_HUMANT625QQEEE T EKKDS 57.28% Swiss-Prot 55.0 (Similarity)View