Regulatory Network in Protein Phosphorylation
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Substrate: TBC1D4

Description: TBC1 domain family member 4 (Akt substrate of 160 kDa) (AS160).

Synonyms: KIAA0603

Ensembl ID: ENSG00000136111

UniprotKB/SwissProt: TBCD4_HUMAN (O60343)

Function: May act as a GTPase-activating protein for Rab family protein(s).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of TBC1D4

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1TBC1D4TBCD4_HUMANS318RSRCS S VTGVQ 27.59% Phospho.ELM 7.0View   
2TBC1D4TBCD4_HUMANS318RSRCS S VTGVQ 27.59%AKT1(PKB) Swiss-Prot 55.0 (Similarity) ViewAnalyzing
3TBC1D4TBCD4_HUMANS341RRRHA S APSHV 34.29%AKT1(PKB) Swiss-Prot 55.0 (Similarity) ViewAnalyzing
4TBC1D4TBCD4_HUMANS341RRRHA S APSHV 34.29% Phospho.ELM 7.0View   
5TBC1D4TBCD4_HUMANS344HASAP S HVQPS 35.69% Swiss-Prot 55.0 View   
6TBC1D4TBCD4_HUMANS344HASAP S HVQPS 35.69% Phospho.ELM 7.0View   
7TBC1D4TBCD4_HUMANS570RSLTS S LENIF 34.17%AKT1(PKB) Swiss-Prot 55.0 (Similarity) ViewAnalyzing
8TBC1D4TBCD4_HUMANS570RSLTS S LENIF 34.17% Phospho.ELM 7.0View   
9TBC1D4TBCD4_HUMANS588RGRLG S VDSFE 27.61% HPRD:18164(in vivo)View   
10TBC1D4TBCD4_HUMANS588RGRLG S VDSFE 27.61% Phospho.ELM 7.0View   
11TBC1D4TBCD4_HUMANS588RGRLG S VDSFE 27.61%AKT1(PKB) Swiss-Prot 55.0  ViewAnalyzing
12TBC1D4TBCD4_HUMANS591LGSVD S FERSN 27.18% Swiss-Prot 55.0 View   
13TBC1D4TBCD4_HUMANT642RRRAH T FSHPP 26.33%AKT_group Phospho.ELM 7.0 ViewAnalyzing
14TBC1D4TBCD4_HUMANT642RRRAH T FSHPP 26.33%AKT1(PKB) Swiss-Prot 55.0  ViewAnalyzing
15TBC1D4TBCD4_HUMANS751RKRTS S TCSNE 32.59% Phospho.ELM 7.0View   
16TBC1D4TBCD4_HUMANS751RKRTS S TCSNE 32.59%AKT1(PKB) Swiss-Prot 55.0 (Similarity) ViewAnalyzing
17TBC1D4TBCD4_HUMANT752KRTSS T CSNES 21.52% Phospho.ELM 7.0View   
18TBC1D4TBCD4_HUMANS754TSSTC S NESLS 43.66% Swiss-Prot 55.0 View   
19TBC1D4TBCD4_HUMANS754TSSTC S NESLS 43.66% HPRD:18164(in vivo)View   
20TBC1D4TBCD4_HUMANS754TSSTC S NESLS 43.66% Phospho.ELM 7.0View   
21TBC1D4TBCD4_HUMANS757TCSNE S LSVGG 30.14% Phospho.ELM 7.0View