|Description: Telomerase reverse transcriptase (EC 188.8.131.52) (Telomerase catalyticsubunit) (HEST2) (Telomerase-associated protein 2) (TP2).|
Synonyms: EST2, TCS1, TRT
Ensembl ID: ENSG00000164362
UniprotKB/SwissProt: TERT_HUMAN (O14746)
Function: Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. It elongates telomeres. It is a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.