|Description: Annexin A2 (Annexin-2) (Annexin II) (Lipocortin II) (Calpactin I heavychain) (Chromobindin-8) (p36) (Protein I) (Placental anticoagulantprotein IV) (PAP-IV).|
Synonyms: ANX2, ANX2L4, CAL1H, LPC2D
Ensembl ID: ENSG00000182718
UniprotKB/SwissProt: ANXA2_HUMAN (P07355)
Function: Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Secreted, extracellular space, extracellular matrix, basement membrane. Melanosome. Note=In the lamina beneath the plasma membrane. Identified by mass spectrometry in melanosome fractions from stage I to stage IV. Translocated from the cytoplasm to the c