Regulatory Network in Protein Phosphorylation
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Substrate: C5AR1

Description: C5a anaphylatoxin chemotactic receptor (C5a-R) (C5aR) (CD88 antigen).

Synonyms: C5AR, C5R1

Ensembl ID: ENSG00000197405

UniprotKB/SwissProt: C5AR_HUMAN (P21730)

Function: Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of C5AR1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1C5AR1C5AR_HUMANS314GRLRK S LPSLL 38.79% Swiss-Prot 55.0 (Probable)View   
2C5AR1C5AR_HUMANS314GRLRK S LPSLL 38.79%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3C5AR1C5AR_HUMANS314GRLRK S LPSLL 38.79% HPRD:00224(in vivo)View   
4C5AR1C5AR_HUMANS317RKSLP S LLRNV 45.38%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
5C5AR1C5AR_HUMANS317RKSLP S LLRNV 45.38% HPRD:00224(in vivo)View   
6C5AR1C5AR_HUMANS317RKSLP S LLRNV 45.38% Swiss-Prot 55.0 (Probable)View   
7C5AR1C5AR_HUMANS327VLTEE S VVRES 21.49% HPRD:00224(in vivo)View   
8C5AR1C5AR_HUMANS327VLTEE S VVRES 21.49% Phospho.ELM 7.0View   
9C5AR1C5AR_HUMANS327VLTEE S VVRES 21.49% Swiss-Prot 55.0 (Probable)View   
10C5AR1C5AR_HUMANS332SVVRE S KSFTR 24.04% HPRD:00224(in vivo)View   
11C5AR1C5AR_HUMANS332SVVRE S KSFTR 24.04% Swiss-Prot 55.0 (Probable)View   
12C5AR1C5AR_HUMANS332SVVRE S KSFTR 24.04%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
13C5AR1C5AR_HUMANS334VRESK S FTRST 40.92% HPRD:00224(in vivo)View   
14C5AR1C5AR_HUMANS334VRESK S FTRST 40.92%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
15C5AR1C5AR_HUMANS334VRESK S FTRST 40.92% Swiss-Prot 55.0 (Probable)View   
16C5AR1C5AR_HUMANS338KSFTR S TVDTM 29.71%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
17C5AR1C5AR_HUMANS338KSFTR S TVDTM 29.71% HPRD:00224(in vivo)View   
18C5AR1C5AR_HUMANS338KSFTR S TVDTM 29.71% Swiss-Prot 55.0 (Probable)View