Regulatory Network in Protein Phosphorylation
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Substrate: CENTA1

Description: Centaurin-alpha-1 (Putative MAPK-activating protein PM25).

Ensembl ID: ENSG00000105963

UniprotKB/SwissProt: CENA1_HUMAN (O75689)

Function: GTPase-activating protein for the ADP ribosylation factor family (Probable). Binds phosphatidylinositol 3,4,5- trisphosphate (PtdInsP3) and inositol 1,3,4,5-tetrakisphosphate (InsP4).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Recruited to the plasma membrane upon epidermal growth factor-dependent activation of phosphatidylinositol 4,5-diphosphate (PtdInsP2) 3-kinase.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CENTA1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CENTA1CENA1_HUMANS87RARFE S KVPSF 35.92%PKC_group Swiss-Prot 55.0  ViewAnalyzing
2CENTA1CENA1_HUMANS87RARFE S KVPSF 35.92%PKCa HPRD:09733(in vitro)  ViewAnalyzing
3CENTA1CENA1_HUMANS87RARFE S KVPSF 35.92%PKCe HPRD:09733(in vitro)  ViewAnalyzing
4CENTA1CENA1_HUMANT276RKRWF T MDDRR 16.84%PKC_group Swiss-Prot 55.0  ViewAnalyzing
5CENTA1CENA1_HUMANT276RKRWF T MDDRR 16.84%PKCa HPRD:09733(in vitro)  ViewAnalyzing
6CENTA1CENA1_HUMANT276RKRWF T MDDRR 16.84%PKCe HPRD:09733(in vitro)  ViewAnalyzing