Regulatory Network in Protein Phosphorylation
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Substrate: DGKD

Description: Diacylglycerol kinase delta (EC 2.7.1.107) (Diglyceride kinase delta)(DGK-delta) (DAG kinase delta) (130 kDa diacylglycerol kinase).

Synonyms: KIAA0145

Ensembl ID: ENSG00000077044

UniprotKB/SwissProt: DGKD_HUMAN (Q16760)

Function: May function as signaling molecule. Isoform 2 may be involved in cell growth and tumorigenesis.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Isoform 2: Cytoplasm. Isoform 1: Membrane; Peripheral membrane protein.
PDB:1R79
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of DGKD

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1DGKDDGKD_HUMANS66TKQNN S FQRSK 30.24%PKCa HPRD:03492(in vitro;in vivo)  ViewAnalyzing
2DGKDDGKD_HUMANS66TKQNN S FQRSK 30.24%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3DGKDDGKD_HUMANS70NSFQR S KRRYF 21.52%PKCa HPRD:03492(in vitro;in vivo)  ViewAnalyzing
4DGKDDGKD_HUMANS70NSFQR S KRRYF 21.52%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing