Regulatory Network in Protein Phosphorylation
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Substrate: GABRB1

Description: Gamma-aminobutyric acid receptor subunit beta-1 precursor (GABA(A)receptor subunit beta-1).

Ensembl ID: ENSG00000163288

UniprotKB/SwissProt: GBRB1_HUMAN (P18505)

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GABRB1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GABRB1GBRB1_HUMANS409YRKPL S SREAY 35.56% HPRD:15924(in vitro)View   
2GABRB1GBRB1_HUMANS434IRRRA S QLKVK 33.95%PKC_group Phospho.ELM 7.0 ViewAnalyzing
3GABRB1GBRB1_HUMANS434IRRRA S QLKVK 33.95%PKA_group Phospho.ELM 7.0 ViewAnalyzing
4GABRB1GBRB1_HUMANS448LTDVN S IDKWS 31.82% Swiss-Prot 55.0 View