Regulatory Network in Protein Phosphorylation
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Substrate: GABRB2

Description: Gamma-aminobutyric acid receptor subunit beta-2 precursor (GABA(A)receptor subunit beta-2).

Ensembl ID: ENSG00000145864

UniprotKB/SwissProt: GBRB2_HUMAN (P47870)

Function: GABA, the major inhibitory neurotransmitter in the vertebrate brain, mediates neuronal inhibition by binding to the GABA/benzodiazepine receptor and opening an integral chloride channel.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GABRB2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GABRB2GBRB2_HUMANY396STMLA Y DASSI 14.21% Swiss-Prot 55.0 (Similarity)View   
2GABRB2GBRB2_HUMANY403ASSIQ Y RKAGL 16.65% Swiss-Prot 55.0 (Similarity)View   
3GABRB2GBRB2_HUMANS434LRRRA S QLKIT 33.95%PKC_group Phospho.ELM 7.0 ViewAnalyzing
4GABRB2GBRB2_HUMANS434LRRRA S QLKIT 33.95% HPRD:02578(in vitro;in vivo)View