Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase PKCi]
Substrate: GEM

Description: GTP-binding protein GEM (GTP-binding mitogen-induced T-cell protein)(RAS-like protein KIR).

Synonyms: KIR

Ensembl ID: ENSG00000164949

UniprotKB/SwissProt: GEM_HUMAN (P55040)

Function: Could be a regulatory protein, possibly participating in receptor-mediated signal transduction at the plasma membrane. Has guanine nucleotide-binding activity but undetectable intrinsic GTPase activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Peripheral membrane protein; Cytoplasmic side.
PDB:2CJW
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GEM

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GEMGEM_HUMANS261QKRKE S MPRKA 36.80%PKCz(PKC zeta) Phospho.ELM 7.0 ViewAnalyzing
2GEMGEM_HUMANS261QKRKE S MPRKA 36.80% HPRD:11553(in vivo)View   
3GEMGEM_HUMANS289KLKSK S CHDLS 24.63% Phospho.ELM 7.0View   
4GEMGEM_HUMANS289KLKSK S CHDLS 24.63% HPRD:11553(in vivo)View