Regulatory Network in Protein Phosphorylation
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Substrate: GFPT1

Description: Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] 1(EC 2.6.1.16) (Glutamine:fructose 6 phosphate amidotransferase 1)(Hexosephosphate aminotransferase 1) (D-fructose-6-phosphateamidotransferase 1) (GFAT 1) (GFAT1).

Synonyms: GFAT, GFPT

Ensembl ID: ENSG00000198380

UniprotKB/SwissProt: GFPT1_HUMAN (Q06210)

Function: Controls the flux of glucose into the hexosamine pathway. Most likely involved in regulating the availability of precursors for N- and O-linked glycosylation of proteins.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GFPT1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GFPT1GFPT1_HUMANS205GTRRG S PLLIG 15.57%PKCa HPRD:00702(in vitro)  ViewAnalyzing
2GFPT1GFPT1_HUMANS205GTRRG S PLLIG 15.57%PKC_group Phospho.ELM 7.0 ViewAnalyzing
3GFPT1GFPT1_HUMANS205GTRRG S PLLIG 15.57%PKA_group Phospho.ELM 7.0 ViewAnalyzing
4GFPT1GFPT1_HUMANS235RTQIG S KFTRW 26.65%PKCa HPRD:00702(in vitro)  ViewAnalyzing
5GFPT1GFPT1_HUMANS235RTQIG S KFTRW 26.65%PKC_group Phospho.ELM 7.0 ViewAnalyzing
6GFPT1GFPT1_HUMANS235RTQIG S KFTRW 26.65%PKA_group Phospho.ELM 7.0 ViewAnalyzing
7GFPT1GFPT1_HUMANS261LSRVD S TTCLF 23.82% Swiss-Prot 55.0 View   
8GFPT1GFPT1_HUMANS261LSRVD S TTCLF 23.82% Phospho.ELM 7.0View