Regulatory Network in Protein Phosphorylation
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Substrate: GPSM2

Description: G-protein-signaling modulator 2 (Mosaic protein LGN).

Synonyms: LGN

Ensembl ID: ENSG00000121957

UniprotKB/SwissProt: GPSM2_HUMAN (P81274)

Function: Plays an important role in spindle pole orientation. Interacts and contributes to the functional activity of G(i) alpha proteins. Acts to stabilize the apical complex during neuroblast divisions.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm. Cytoplasm, cell cortex. Note=Localizes in the cytoplasm in the interphase and at cell periphery in the metaphase.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GPSM2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GPSM2GPSM2_HUMANS125RHLDI S RELND 21.26%PKG_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
2GPSM2GPSM2_HUMANS345KHLEI S REVGD 17.02%PKG_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
3GPSM2GPSM2_HUMANS401LGRRH S MENME 26.44%PKA_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
4GPSM2GPSM2_HUMANS494LSRFQ S NRMDD 24.56%PKC_group Swiss-Prot 55.0 (Potential) ViewAnalyzing
5GPSM2GPSM2_HUMANS600VKCQG S RLDDQ 12.09%PKG_group Swiss-Prot 55.0 (Potential) ViewAnalyzing