Regulatory Network in Protein Phosphorylation
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Substrate: GSK3A

Description: Glycogen synthase kinase-3 alpha (EC 2.7.11.26) (GSK-3 alpha).

Ensembl ID: ENSG00000105723

UniprotKB/SwissProt: GSK3A_HUMAN (P49840)

Function: Implicated in the hormonal control of several regulatory proteins including glycogen synthase, MYB and the transcription factor JUN (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
PDB:2DFM
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of GSK3A

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06% Swiss-Prot 55.0 View   
2GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%AKT1 HPRD:06002(in vitro;in vivo)  ViewAnalyzing
3GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKA_group Phospho.ELM 7.0 ViewAnalyzing
4GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKCa HPRD:06002(in vitro;in vivo)  ViewAnalyzing
5GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKCg HPRD:06002(in vitro;in vivo)  ViewAnalyzing
6GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKCd HPRD:06002(in vitro;in vivo)  ViewAnalyzing
7GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKD3 HPRD:06002(in vitro;in vivo)  ViewAnalyzing
8GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKC_group Phospho.ELM 7.0 ViewAnalyzing
9GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%SGK1 HPRD:06002(in vivo)  ViewAnalyzing
10GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%SGK3 HPRD:06002(in vitro;in vivo)  ViewAnalyzing
11GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKACa HPRD:06002(in vitro;in vivo)  ViewAnalyzing
12GSK3AGSK3A_HUMANS21RARTS S FAEPG 28.06%PKCb HPRD:06002(in vitro;in vivo)  ViewAnalyzing
13GSK3AGSK3A_HUMANY279EPNVS Y ICSRY 11.15% Swiss-Prot 55.0 View   
14GSK3AGSK3A_HUMANY279EPNVS Y ICSRY 11.15% Phospho.ELM 7.0View