|Description: Heart- and neural crest derivatives-expressed protein 1(Extraembryonic tissues, heart, autonomic nervous system and neuralcrest derivatives-expressed protein 1) (eHAND).|
Ensembl ID: ENSG00000113196
UniprotKB/SwissProt: HAND1_HUMAN (O96004)
Function: Plays an essential role in early trophoblast differentiation and in cardiac morphogenesis. In the adult, could be required for ongoing expression of cardiac-specific genes. Binds the DNA sequence 5'-NRTCTG-3' (non-canonical E-box) (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (By similarity).