Regulatory Network in Protein Phosphorylation
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Substrate: HSPB8

Description: Heat shock protein beta-8 (HspB8) (Alpha-crystallin C chain) (Smallstress protein-like protein HSP22) (E2-induced gene 1 protein)(Protein kinase H11).

Synonyms: CRYAC, E2IG1, HSP22

Ensembl ID: ENSG00000152137

UniprotKB/SwissProt: HSPB8_HUMAN (Q9UJY1)

Function: Displays temperature-dependent chaperone activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of HSPB8

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1HSPB8HSPB8_HUMANS14SCHYP S RLRRD 36.46%PKC_group Phospho.ELM 7.0 ViewAnalyzing
2HSPB8HSPB8_HUMANS14SCHYP S RLRRD 36.46%PKCa HPRD:06420(in vitro)  ViewAnalyzing
3HSPB8HSPB8_HUMANS27RDSPL S SRLLD 19.45%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
4HSPB8HSPB8_HUMANS27RDSPL S SRLLD 19.45%Erk1 HPRD:06420(in vitro)  ViewAnalyzing
5HSPB8HSPB8_HUMANT63SAWPG T LRSGM 18.21%PKC_group Swiss-Prot 55.0 (in vitro) ViewAnalyzing
6HSPB8HSPB8_HUMANT63SAWPG T LRSGM 18.21%PKC_group Phospho.ELM 7.0 ViewAnalyzing
7HSPB8HSPB8_HUMANT63SAWPG T LRSGM 18.21%PKCa HPRD:06420(in vitro)  ViewAnalyzing
8HSPB8HSPB8_HUMANT87PAEGR T PPPFP 51.51%Erk1(MAPK3) Phospho.ELM 7.0 ViewAnalyzing
9HSPB8HSPB8_HUMANT87PAEGR T PPPFP 51.51%Erk1 HPRD:06420(in vitro)  ViewAnalyzing