|Description: Integrin beta-7 precursor.|
Ensembl ID: ENSG00000139626
UniprotKB/SwissProt: ITB7_HUMAN (P26010)
Function: Integrin alpha-4/beta-7 (Peyer patches-specific homing receptor LPAM-1) is expected to play a role in adhesive interactions of leukocytes. It is a receptor for fibronectin and recognizes one or more domains within the alternatively spliced CS-1 region of fibronectin. Integrin alpha-4/beta-7 is also a receptor for MADCAM1 and VCAM1. It recognizes the sequence L-D-T in MADCAM1. Integrin alpha-E/beta-7 (HML-1) is a receptor for E- cadherin.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Single-pass type I membrane protein.