Regulatory Network in Protein Phosphorylation
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Substrate: KCNC4

Description: Potassium voltage-gated channel subfamily C member 4 (Voltage-gatedpotassium channel subunit Kv3.4) (KSHIIIC).

Ensembl ID: ENSG00000116396

UniprotKB/SwissProt: KCNC4_HUMAN (Q03721)

Function: This protein mediates the voltage-dependent potassium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a potassium-selective channel through which potassium ions may pass in accordance with their electrochemical gradient.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of KCNC4

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1KCNC4KCNC4_HUMANS8SSVCV S SYRGR 19.27% Swiss-Prot 55.0 View   
2KCNC4KCNC4_HUMANS8SSVCV S SYRGR 19.27%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3KCNC4KCNC4_HUMANS8SSVCV S SYRGR 19.27%PKCb(PKC beta) Phospho.ELM 7.0 ViewAnalyzing
4KCNC4KCNC4_HUMANS8SSVCV S SYRGR 19.27%PKCg(PKC gamma) Phospho.ELM 7.0 ViewAnalyzing
5KCNC4KCNC4_HUMANS9SVCVS S YRGRK 9.84%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
6KCNC4KCNC4_HUMANS9SVCVS S YRGRK 9.84%PKCb(PKC beta) Phospho.ELM 7.0 ViewAnalyzing
7KCNC4KCNC4_HUMANS9SVCVS S YRGRK 9.84%PKCg(PKC gamma) Phospho.ELM 7.0 ViewAnalyzing
8KCNC4KCNC4_HUMANS9SVCVS S YRGRK 9.84% Swiss-Prot 55.0 View   
9KCNC4KCNC4_HUMANS15YRGRK S GNKPP 46.36%PKCg(PKC gamma) Phospho.ELM 7.0 ViewAnalyzing
10KCNC4KCNC4_HUMANS15YRGRK S GNKPP 46.36% Swiss-Prot 55.0 View   
11KCNC4KCNC4_HUMANS15YRGRK S GNKPP 46.36%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
12KCNC4KCNC4_HUMANS15YRGRK S GNKPP 46.36%PKCb(PKC beta) Phospho.ELM 7.0 ViewAnalyzing
13KCNC4KCNC4_HUMANS21GNKPP S KTCLK 49.47%PKCb(PKC beta) Phospho.ELM 7.0 ViewAnalyzing
14KCNC4KCNC4_HUMANS21GNKPP S KTCLK 49.47%PKCg(PKC gamma) Phospho.ELM 7.0 ViewAnalyzing
15KCNC4KCNC4_HUMANS21GNKPP S KTCLK 49.47% Swiss-Prot 55.0 View   
16KCNC4KCNC4_HUMANS21GNKPP S KTCLK 49.47%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing