Regulatory Network in Protein Phosphorylation
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Substrate: PLAU

Description: Urokinase-type plasminogen activator precursor (EC 3.4.21.73) (uPA)(U-plasminogen activator) [Contains: Urokinase-type plasminogenactivator long chain A; Urokinase-type plasminogen activator shortchain A; Urokinase-type plasminogen activator chain B].

Ensembl ID: ENSG00000122861

UniprotKB/SwissProt: UROK_HUMAN (P00749)

Function: Specifically cleave the zymogen plasminogen to form the active enzyme plasmin.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Secreted.
PDB:1C5W
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PLAU

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PLAUUROK_HUMANS158DGKKP S SPPEE 65.44% Swiss-Prot 55.0 View   
2PLAUUROK_HUMANS158DGKKP S SPPEE 65.44%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3PLAUUROK_HUMANS323FGKEN S TDYLY 24.60% Swiss-Prot 55.0 View   
4PLAUUROK_HUMANS323FGKEN S TDYLY 24.60%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing