Regulatory Network in Protein Phosphorylation
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Substrate: PPP1R14D

Description: Protein phosphatase 1 regulatory subunit 14D (Gastrointestinal andbrain-specific PP1-inhibitory protein 1) (GBPI-1).

Synonyms: GBPI

Ensembl ID: ENSG00000166143

UniprotKB/SwissProt: PP14D_HUMAN (Q9NXH3)

Function: Inhibitor of PPP1CA. Has inhibitory activity only when phosphorylated, creating a molecular switch for regulating the phosphorylation status of PPP1CA substrates and smooth muscle contraction.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cytoplasm (Probable).
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PPP1R14D

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PPP1R14DPP14D_HUMANT58RPSRL T VKYDR 17.53% Swiss-Prot 55.0 View   
2PPP1R14DPP14D_HUMANT58RPSRL T VKYDR 17.53%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
3PPP1R14DPP14D_HUMANT58RPSRL T VKYDR 17.53%PKA_group Phospho.ELM 7.0 ViewAnalyzing