|Description: Prostaglandin E2 receptor EP4 subtype (Prostanoid EP4 receptor) (PGEreceptor, EP4 subtype).|
Ensembl ID: ENSG00000171522
UniprotKB/SwissProt: PE2R4_HUMAN (P35408)
Function: Receptor for prostaglandin E2 (PGE2). The activity of this receptor is mediated by G(s) proteins that stimulate adenylate cyclase. Has a relaxing effect on smooth muscle. May play an important role in regulating renal hemodynamics, intestinal epithelial transport, adrenal aldosterone secretion, and uterine function.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein.