Regulatory Network in Protein Phosphorylation
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Substrate: PTGIR

Description: Prostacyclin receptor (Prostanoid IP receptor) (PGI receptor)(Prostaglandin I2 receptor).

Synonyms: PRIPR

Ensembl ID: ENSG00000160013

UniprotKB/SwissProt: PI2R_HUMAN (P43119)

Function: Receptor for prostacyclin (prostaglandin I2 or PGI2). The activity of this receptor is mediated by G(s) proteins which activate adenylate cyclase.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Cell membrane; Multi-pass membrane protein.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of PTGIR

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1PTGIRPI2R_HUMANS328LSQLA S GRRDP 41.23%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
2PTGIRPI2R_HUMANS328LSQLA S GRRDP 41.23%PKCa HPRD:08959(in vitro)  ViewAnalyzing