|Description: Regulator of G-protein signaling 19 (RGS19) (G-alpha-interactingprotein) (GAIP).|
Synonyms: GAIP, GNAI3IP
Ensembl ID: ENSG00000171700
UniprotKB/SwissProt: RGS19_HUMAN (P49795)
Function: Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds to G-alpha subfamily 1 members, with the order G(i)a3 > G(i)a1 > G(o)a >> G(z)a/G(i)a2. Activity on G(z)-alpha is inhibited by phosphorylation and palmitoylation of the G-protein.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Membrane; Lipid-anchor.