Regulatory Network in Protein Phosphorylation
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Substrate: RPS6KB2

Description: Ribosomal protein S6 kinase beta-2 (EC 2.7.11.1) (S6K2) (70 kDaribosomal protein S6 kinase 2) (p70-S6KB) (p70 ribosomal S6 kinasebeta) (p70 S6Kbeta) (p70 S6 kinase beta) (S6K-beta) (p70-beta) (S6kinase-related kinase) (SRK) (Serine/threonine-protein kinase 14beta).

Synonyms: STK14B

Ensembl ID: ENSG00000175634

UniprotKB/SwissProt: KS6B2_HUMAN (Q9UBS0)

Function: Phosphorylates specifically ribosomal protein S6.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of RPS6KB2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1RPS6KB2KS6B2_HUMANS15ETEEG S EGEGE 45.79% Swiss-Prot 55.0 View   
2RPS6KB2KS6B2_HUMANS15ETEEG S EGEGE 45.79% Phospho.ELM 7.0View   
3RPS6KB2KS6B2_HUMANT228GAVTH T FCGTI 15.97%FRAP HPRD:10203(in vitro)  ViewAnalyzing
4RPS6KB2KS6B2_HUMANT228GAVTH T FCGTI 15.97%PDK1 HPRD:10203(in vitro)  ViewAnalyzing
5RPS6KB2KS6B2_HUMANS356SEEDV S QFDTR 37.13% Swiss-Prot 55.0 View   
6RPS6KB2KS6B2_HUMANS370QTPVD S PDDTA 30.38%FRAP HPRD:10203(in vitro)  ViewAnalyzing
7RPS6KB2KS6B2_HUMANS370QTPVD S PDDTA 30.38%PDK1 HPRD:10203(in vitro)  ViewAnalyzing
8RPS6KB2KS6B2_HUMANT388AFLGF T YVAPS 18.45%FRAP HPRD:10203(in vitro)  ViewAnalyzing
9RPS6KB2KS6B2_HUMANT388AFLGF T YVAPS 18.45%PDK1 HPRD:10203(in vitro)  ViewAnalyzing
10RPS6KB2KS6B2_HUMANT388AFLGF T YVAPS 18.45%FRAP(mTOR) Phospho.ELM 7.0 ViewAnalyzing
11RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCz(PKC zeta) Phospho.ELM 7.0 ViewAnalyzing
12RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCa(PKC alpha) Phospho.ELM 7.0 ViewAnalyzing
13RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCd(PKC delta) Phospho.ELM 7.0 ViewAnalyzing
14RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCg(PKC gamma) Phospho.ELM 7.0 ViewAnalyzing
15RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCe(PKC epsilon) Phospho.ELM 7.0 ViewAnalyzing
16RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCi Phospho.ELM 7.0  ViewAnalyzing
17RPS6KB2KS6B2_HUMANS473SGTKK S KRGRG 29.19%PKCb(PKC beta) Phospho.ELM 7.0 ViewAnalyzing