|Description: Afadin (Protein AF-6).|
Ensembl ID: ENSG00000130396
UniprotKB/SwissProt: AFAD_HUMAN (P55196)
Function: Belongs to an adhesion system, probably together with the E-cadherin-catenin system, which plays a role in the organization of homotypic, interneuronal and heterotypic cell-cell adherens junctions (AJs). Nectin- and actin-filament-binding protein that connects nectin to the actin cytoskeleton.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cell junction, adherens junction. Note=Not found at cell-matrix AJs.