Regulatory Network in Protein Phosphorylation
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Substrate: BRSK2

Description: BR serine/threonine-protein kinase 2 (EC 2.7.11.1) (Serine/threonine-protein kinase 29) (Serine/threonine kinase SAD-A).

Synonyms: C11orf7, PEN11B, STK29

Ensembl ID: ENSG00000174672

UniprotKB/SwissProt: BRSK2_HUMAN (Q8IWQ3)

Function: Required for the polarization of forebrain neurons which endows axons and dendrites with distinct properties, possibly by locally regulating phosphorylation of microtubule-associated proteins (By similarity).

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of BRSK2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1BRSK2BRSK2_HUMANT174DSLLE T SCGSP 29.32% Swiss-Prot 55.0 View   
2BRSK2BRSK2_HUMANT174DSLLE T SCGSP 29.32%LKB1(STK11) Phospho.ELM 7.0 ViewAnalyzing
3BRSK2BRSK2_HUMANS178ETSCG S PHYAC 16.90% Swiss-Prot 55.0 (Similarity)View   
4BRSK2BRSK2_HUMANT422SSGLS T SPLSS 39.13% Swiss-Prot 55.0 (Similarity)View