|Description: Serine/threonine-protein kinase SNF1-like kinase 2 (EC 188.8.131.52) (Qin-induced kinase) (Salt-inducible protein kinase 2) (SIK-2) (SIK2).|
Synonyms: KIAA0781, QIK, SIK2
Ensembl ID: ENSG00000170145
UniprotKB/SwissProt: SN1L2_HUMAN (Q9H0K1)
Function: Phosphorylates 'Ser-794' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Cytoplasm (By similarity).