Regulatory Network in Protein Phosphorylation
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Substrate: STRAD

Description: STE20-related adapter protein (STRAD alpha) (Serologically definedbreast cancer antigen NY-BR-96).

Synonyms: LYK5

Ensembl ID: ENSG00000125695

UniprotKB/SwissProt: STRAD_HUMAN (Q7RTN6)

Function: Pseudokinase which, in complex with CAB39, binds to and activates STK11. Relocates STK11 from the nucleus to the cytoplasm. Plays an essential role in STK11-mediated G1 cell cycle arrest.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus. Cytoplasm.
PDB:1UPK
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of STRAD

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1STRADSTRAD_HUMANT329SDSLT T STPRP 35.58%LKB1(STK11) Swiss-Prot 55.0  ViewAnalyzing
2STRADSTRAD_HUMANT419IFGLV T NLEEL 38.85%LKB1(STK11) Swiss-Prot 55.0  ViewAnalyzing