|Description: Mitotic checkpoint serine/threonine-protein kinase BUB1 (EC 220.127.116.11)(hBUB1) (BUB1A).|
Ensembl ID: ENSG00000169679
UniprotKB/SwissProt: BUB1_HUMAN (O43683)
Function: Involved in cell cycle checkpoint enforcement. Can interact and phosphorylate BUB3.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus (By similarity). Kinetochore (By similarity). Note=Nuclear in interphase cells. Kinetochore localization is required for normal mitotic timing and checkpoint response to spindle damage (By similarity).