Regulatory Network in Protein Phosphorylation
[Home] [About] [Browse Kinome] [Phosphorylation Prediction] [Expression Analysis] [Statistics] [Help] Version 1.0

[Back to Kinase CDK2]
Substrate: CDC16

Description: Cell division cycle protein 16 homolog (CDC16Hs) (Anaphase-promotingcomplex subunit 6) (APC6) (Cyclosome subunit 6).

Ensembl ID: ENSG00000130177

UniprotKB/SwissProt: CDC16_HUMAN (Q13042)

Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Centrosome. Note=Colocalizes with CDC27 to the centrosome at all stages of the cell cycle and to the mitotic spindle.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CDC16

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CDC16CDC16_HUMANS112YLKDE S GFKDP 60.71% Swiss-Prot 55.0 View   
2CDC16CDC16_HUMANS112YLKDE S GFKDP 60.71% Phospho.ELM 7.0View   
3CDC16CDC16_HUMANS490IGYIH S LMGNF 15.53% Swiss-Prot 55.0 View   
4CDC16CDC16_HUMANS490IGYIH S LMGNF 15.53% Phospho.ELM 7.0View   
5CDC16CDC16_HUMANS560LKNII S PPWDF 22.55% Swiss-Prot 55.0 View   
6CDC16CDC16_HUMANS560LKNII S PPWDF 22.55% HPRD:04587(in vivo)View   
7CDC16CDC16_HUMANS560LKNII S PPWDF 22.55%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
8CDC16CDC16_HUMANT581EETGL T PLETS 27.46%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
9CDC16CDC16_HUMANT581EETGL T PLETS 27.46% HPRD:04587(in vivo)View   
10CDC16CDC16_HUMANT581EETGL T PLETS 27.46% Swiss-Prot 55.0 View   
11CDC16CDC16_HUMANS595PDSRP S LEETF 47.50% Swiss-Prot 55.0 View   
12CDC16CDC16_HUMANS595PDSRP S LEETF 47.50% Phospho.ELM 7.0View   
13CDC16CDC16_HUMANT599PSLEE T FEIEM 19.72% Swiss-Prot 55.0 View   
14CDC16CDC16_HUMANT599PSLEE T FEIEM 19.72% Phospho.ELM 7.0View