Regulatory Network in Protein Phosphorylation
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Substrate: CDC23

Description: Cell division cycle protein 23 homolog (Anaphase-promoting complexsubunit 8) (APC8) (Cyclosome subunit 8).

Ensembl ID: ENSG00000094880

UniprotKB/SwissProt: CDC23_HUMAN (Q9UJX2)

Function: Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CDC23

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CDC23CDC23_HUMANY267QIAVA Y HNIRD 6.71% Phospho.ELM 7.0View   
2CDC23CDC23_HUMANY267QIAVA Y HNIRD 6.71% Swiss-Prot 55.0 View   
3CDC23CDC23_HUMANT556RNQGE T PTTEV 32.53% Swiss-Prot 55.0 View   
4CDC23CDC23_HUMANT556RNQGE T PTTEV 32.53%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
5CDC23CDC23_HUMANT556RNQGE T PTTEV 32.53%PLK1 Phospho.ELM 7.0  ViewAnalyzing
6CDC23CDC23_HUMANT559GETPT T EVPAP 35.87%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
7CDC23CDC23_HUMANT559GETPT T EVPAP 35.87% Swiss-Prot 55.0 View   
8CDC23CDC23_HUMANT559GETPT T EVPAP 35.87%PLK1 Phospho.ELM 7.0  ViewAnalyzing
9CDC23CDC23_HUMANS572LPASL S ANNTP 26.84% HPRD:07221(in vitro)View   
10CDC23CDC23_HUMANS572LPASL S ANNTP 26.84% Swiss-Prot 55.0 (Similarity)View   
11CDC23CDC23_HUMANT576LSANN T PTRRV 26.33%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
12CDC23CDC23_HUMANS582PTRRV S PLNLS 23.12% Phospho.ELM 7.0View   
13CDC23CDC23_HUMANS582PTRRV S PLNLS 23.12% Swiss-Prot 55.0 View   
14CDC23CDC23_HUMANS587SPLNL S SVTP 22.99% Phospho.ELM 7.0View   
15CDC23CDC23_HUMANS588PLNLS S VTP 32.93% HPRD:07221(in vivo)View   
16CDC23CDC23_HUMANT590NLSSV T25.81% Phospho.ELM 7.0View   
17CDC23CDC23_HUMANT590NLSSV T25.81% Swiss-Prot 55.0 View   
18CDC23CDC23_HUMANT590NLSSV T25.81% HPRD:07221(in vivo)View