Regulatory Network in Protein Phosphorylation
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Substrate: CDC25B

Description: M-phase inducer phosphatase 2 (EC 3.1.3.48) (Dual specificityphosphatase Cdc25B).

Synonyms: CDC25HU2

Ensembl ID: ENSG00000101224

UniprotKB/SwissProt: MPIP2_HUMAN (P30305)

Function: Tyrosine protein phosphatase which functions as a dosage-dependent inducer of mitotic progression. Directly dephosphorylates CDC2 and stimulates its kinase activity. The three isoforms seem to have a different level of activity.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Centrosome.
PDB:1CWR
Protein Domain and Phosphorylation Sites: