Regulatory Network in Protein Phosphorylation
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Substrate: CDX2

Description: Homeobox protein CDX-2 (Caudal-type homeobox protein 2) (CDX-3).

Synonyms: CDX3

Ensembl ID: ENSG00000165556

UniprotKB/SwissProt: CDX2_HUMAN (Q99626)

Function: Involved in the transciptional regulation of multiple genes expressed in the intestinal epithelium. Important in broad range of functions from early differentiation to maintenance of the intestinal epithelial lining of both the small and large intestine.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Nucleus.
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CDX2

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CDX2CDX2_HUMANS60LDSAQ S PGPSW 31.38% Swiss-Prot 55.0 (Similarity)View   
2CDX2CDX2_HUMANS60LDSAQ S PGPSW 31.38% HPRD:02622(in vivo)View   
3CDX2CDX2_HUMANS60LDSAQ S PGPSW 31.38% Phospho.ELM 7.0View   
4CDX2CDX2_HUMANS283VPEPL S PVSSL 33.69%CDK2 HPRD:02622(in vitro;in vivo)  ViewAnalyzing
5CDX2CDX2_HUMANS283VPEPL S PVSSL 33.69%GSK3B HPRD:02622(in vitro)  ViewAnalyzing
6CDX2CDX2_HUMANS283VPEPL S PVSSL 33.69%p38a HPRD:02622(in vitro)  ViewAnalyzing
7CDX2CDX2_HUMANS287LSPVS S LQASV 25.41%GSK3B HPRD:02622(in vitro)  ViewAnalyzing
8CDX2CDX2_HUMANS287LSPVS S LQASV 25.41%p38a HPRD:02622(in vitro)  ViewAnalyzing
9CDX2CDX2_HUMANS287LSPVS S LQASV 25.41%CDK2 HPRD:02622(in vitro;in vivo)  ViewAnalyzing
10CDX2CDX2_HUMANS291SSLQA S VSGSV 12.12%CDK2 HPRD:02622(in vitro;in vivo)  ViewAnalyzing
11CDX2CDX2_HUMANS291SSLQA S VSGSV 12.12%GSK3B HPRD:02622(in vitro)  ViewAnalyzing
12CDX2CDX2_HUMANS291SSLQA S VSGSV 12.12%p38a HPRD:02622(in vitro)  ViewAnalyzing
13CDX2CDX2_HUMANS295ASVSG S VPGVL 20.03%p38a HPRD:02622(in vitro)  ViewAnalyzing
14CDX2CDX2_HUMANS295ASVSG S VPGVL 20.03%CDK2 HPRD:02622(in vitro;in vivo)  ViewAnalyzing
15CDX2CDX2_HUMANS295ASVSG S VPGVL 20.03%GSK3B HPRD:02622(in vitro)  ViewAnalyzing