Regulatory Network in Protein Phosphorylation
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Substrate: CEP55

Description: Centrosomal protein of 55 kDa (Cep55) (Up-regulated in colon cancer6).

Synonyms: C10orf3, URCC6

Ensembl ID: ENSG00000138180

UniprotKB/SwissProt: CEP55_HUMAN (Q53EZ4)

Function: Plays a role in mitotic exit and cytokinesis. Not required for microtubule nucleation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization: Centrosome, centriole. Note=Present at the centrosomes at interphase. A small portion is associated preferentially with the mother centriole, whereas the majority localizes to the pericentriolar material. During mitosis, loss of affinity for the centroso
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CEP55

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CEP55CEP55_HUMANS425EKVAA S PKSPT 24.11%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
2CEP55CEP55_HUMANS425EKVAA S PKSPT 24.11%Erk2 HPRD:12569(in vitro;in vivo)  ViewAnalyzing
3CEP55CEP55_HUMANS425EKVAA S PKSPT 24.11%CDC2 Swiss-Prot 55.0   ViewAnalyzing
4CEP55CEP55_HUMANS425EKVAA S PKSPT 24.11% Phospho.ELM 7.0View   
5CEP55CEP55_HUMANS425EKVAA S PKSPT 24.11%CDC2 HPRD:12569(in vitro;in vivo)  ViewAnalyzing
6CEP55CEP55_HUMANS428AASPK S PTAAL 30.76%Erk2(MAPK1) Swiss-Prot 55.0  ViewAnalyzing
7CEP55CEP55_HUMANS428AASPK S PTAAL 30.76%CDC2 HPRD:12569(in vitro;in vivo)  ViewAnalyzing
8CEP55CEP55_HUMANS428AASPK S PTAAL 30.76% Phospho.ELM 7.0View   
9CEP55CEP55_HUMANS428AASPK S PTAAL 30.76%Erk2 HPRD:12569(in vitro;in vivo)  ViewAnalyzing
10CEP55CEP55_HUMANS428AASPK S PTAAL 30.76%CDC2 Swiss-Prot 55.0   ViewAnalyzing
11CEP55CEP55_HUMANS436AALNE S LVECP 36.32%PLK1 HPRD:12569(in vitro)  ViewAnalyzing
12CEP55CEP55_HUMANS436AALNE S LVECP 36.32%PLK1 Swiss-Prot 55.0   ViewAnalyzing
13CEP55CEP55_HUMANS436AALNE S LVECP 36.32% Phospho.ELM 7.0View