Regulatory Network in Protein Phosphorylation
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Substrate: CSNK2A1

Description: Casein kinase II subunit alpha (EC (CK II).

Synonyms: CK2A1

Ensembl ID: ENSG00000101266

UniprotKB/SwissProt: CSK21_HUMAN (P68400)

Function: Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha' chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates 'Ser-392' of p53/TP53 following UV irradiation.

Other Modifications: View all modification sites in dbPTM

Protein Subcellular Localization:
Protein Domain and Phosphorylation Sites:

The phosphorylated sites of CSNK2A1

No.SubstrateUniProtKB IDPositionPhosphoPeptideSolvent AccessibilityCatalytic kinaseSourceComputational Annotation of Catalytic KinaseInteracting PartnersExpression Analysis
1CSNK2A1CSK21_HUMANY182GLAEF Y HPGQE 9.90% HPRD:00277(in vitro)View   
2CSNK2A1CSK21_HUMANY255GTEDL Y DYIDK 21.01%Lyn Phospho.ELM 7.0  ViewAnalyzing
3CSNK2A1CSK21_HUMANY255GTEDL Y DYIDK 21.01%Fgr Phospho.ELM 7.0  ViewAnalyzing
4CSNK2A1CSK21_HUMANT344MPGGS T PVSSA 30.86%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
5CSNK2A1CSK21_HUMANT344MPGGS T PVSSA 30.86%CDK_group Phospho.ELM 7.0 ViewAnalyzing
6CSNK2A1CSK21_HUMANT344MPGGS T PVSSA 30.86%CDC2 HPRD:00277(in vitro)  ViewAnalyzing
7CSNK2A1CSK21_HUMANT360ISSVP T PSPLG 33.95%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
8CSNK2A1CSK21_HUMANT360ISSVP T PSPLG 33.95%CDC2 HPRD:00277(in vitro)  ViewAnalyzing
9CSNK2A1CSK21_HUMANT360ISSVP T PSPLG 33.95%CDK_group Phospho.ELM 7.0 ViewAnalyzing
10CSNK2A1CSK21_HUMANS362SVPTP S PLGPL 34.92%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
11CSNK2A1CSK21_HUMANS362SVPTP S PLGPL 34.92%CDC2 HPRD:00277(in vitro)  ViewAnalyzing
12CSNK2A1CSK21_HUMANS362SVPTP S PLGPL 34.92%CDK_group Phospho.ELM 7.0 ViewAnalyzing
13CSNK2A1CSK21_HUMANS370GPLAG S PVIAA 15.47%CDC2(CDK1) Phospho.ELM 7.0 ViewAnalyzing
14CSNK2A1CSK21_HUMANS370GPLAG S PVIAA 15.47%CDC2 HPRD:00277(in vitro)  ViewAnalyzing
15CSNK2A1CSK21_HUMANS370GPLAG S PVIAA 15.47%CDK_group Phospho.ELM 7.0 ViewAnalyzing