|Description: Homeobox protein cut-like 1 (CCAAT displacement protein) (CDP).|
Ensembl ID: ENSG00000160967
UniprotKB/SwissProt: CUTL1_HUMAN (P39880)
Function: Probably has a broad role in mammalian development as a repressor of developmentally regulated gene expression. May act by preventing binding of positively-activing CCAAT factors to promoters. Component of nf-munr repressor; binds to the matrix attachment regions (MARs) (5' and 3') of the immunoglobulin heavy chain enhancer. Represses T-cell receptor (TCR) beta enhancer function by binding to MARbeta, an ATC-rich DNA sequence located upstream of the TCR beta enhancer (By similarity).
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus.