|Description: Disks large-associated protein DLG7 (Discs large homolog 7) (Hepatomaup-regulated protein) (HURP).|
Ensembl ID: ENSG00000126787
UniprotKB/SwissProt: DLG7_HUMAN (Q15398)
Function: Potential cell cycle regulator that may play a role in carcinogenesis of cancer cells. Mitotic phosphoprotein regulated by the ubiquitin-proteasome pathway. Key regulator of adherens junction integrity and differentiation that may be involved in CDH1-mediated adhesion and signaling in epithelial cells.
Other Modifications: View all modification sites in dbPTM
Protein Subcellular Localization: Nucleus. Cytoplasm. Note=Localizes to the spindle poles in mitotic cells. Colocalizes with CDH1 at sites of cell-cell contact in intestinal epithelial cells.